Development of Novel Therapeutics for Cancer and Dementia

Student First Name

Jose

Student Last Name

Oregel

School Affiliation (multiple allowed)

School of Mathematical and Natural Sciences

Is the research affiliated with NCUIRE

Yes

Project Description

Evaluation of 23 novel rexinoids for biological selectivity and potency compared to the (control) bexarotene therapeutic in order to identify synthetic ligands that possess a high affinity for RXR and activate RXR-mediated transcription.